2025
"Research is the distance between an idea and its realization."
- David Sarnoff
Developing a Unique Bioactive Lipid Signature as a Potential Liquid Biopsy Tool for Early Detection of Gallbladder Cancer (GBC).
This project aims to develop a non-invasive liquid biopsy–based diagnostic approach by identifying a unique bioactive lipid signature that can enable early detection and improved clinical management of gallbladder cancer. Using advanced lipidomic and mass spectrometry–based profiling, the study aims to identify and validate a panel of circulating bioactive lipids that distinguish early-stage GBC from healthy individuals and benign gallbladder conditions.
The project also explores how these lipid alterations relate to tumour biology, inflammation, and disease progression. By integrating lipid signatures with clinical parameters, this research seeks to establish a sensitive and specific liquid biopsy tool for gallbladder cancer. The ultimate goal is to enable earlier diagnosis, risk minimization, and better patient outcomes, particularly in populations with a high incidence of GBC.
